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Efficient insertion from an internal long terminal repeat (LTR)-LTR sequence on a reticuloendotheliosis virus vector is imprecise and cell specific.

To examine the fidelity and efficiency of integration from a covalently closed long terminal repeat (LTR)-LTR sequence in vivo, we isolated individual spleen necrosis virus proviruses that arose following infection of chicken embryo fibroblasts (CEFs) and sequenced the provirus-cell DNA junctions. S...

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Bibliografski detalji
Izdano u:J Virol
Glavni autori: Panganiban, A T, Talbot, K J
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1993
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237527/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8382311/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.3.1564-1571.1993
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