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Activation of AKT/PKB in breast cancer predicts a worse outcome among endocrine treated patients
Akt/PKB is a serine/threonine protein kinase that regulates cell cycle progression, apoptosis and growth factor mediated cell survival in association with tyrosine kinase receptors. The protein is a downstream effector of erbB-2 with implications in breast cancer progression and drug resistance in v...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2375266/ https://ncbi.nlm.nih.gov/pubmed/11870534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600126 |
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