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Phenotypic characteristics of colo-rectal cancer in I1307K APC germline mutation carriers compared with sporadic cases

The I1307K APC germline mutation is associated with an increased risk to colo-rectal cancer (CRC). Whether and to what extent the phenotype of CRC in mutation carriers differs from sporadic cases, remains unknown. To gain insight into this issue, we analysed 307 unselected Israeli patients with CRC,...

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Autors principals: Figer, A, Shtoyerman-Chen, R, Tamir, A, Geva, R, Irmin, L, Flex, D, Theodor, L, Sulkes, A, Sadetzki, S, Bar-Meir, S, Friedman, E
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375261/
https://ncbi.nlm.nih.gov/pubmed/11720476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.2093
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