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Mxi1 inhibits the proliferation of U87 glioma cells through down-regulation of cyclin B1 gene expression
Mxi1 is a Mad family member that plays a role in cell proliferation and differentiation. To test the role of Mxi1 on tumorigenesis of glioma cells we transfected a CMV-driven MXI1 cDNA in U87 human glioblastoma cells. Two clones were isolated expressing MXI1 levels 18- and 3.5-fold higher than wild-...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2002
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2375210/ https://ncbi.nlm.nih.gov/pubmed/11875718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600065 |
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