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Reduced PTEN expression in the pancreas overexpressing transforming growth factor-beta 1
PTEN is a candidate tumour suppressor gene and frequently mutated in multiple cancers, however, not in pancreatic cancer. Recently, it has been demonstrated that PTEN expression is regulated by TGF-β1. Using TGF-β1 transgenic mice (n=7) and wildtype littermates (n=6), as well as pancreatic tissues o...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2002
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2375189/ https://ncbi.nlm.nih.gov/pubmed/11870516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600031 |
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