Two mechanisms of soluble CD4 (sCD4)-mediated inhibition of human immunodeficiency virus type 1 (HIV-1) infectivity and their relation to primary HIV-1 isolates with reduced sensitivity to sCD4.

Ítems similars

• Virions of primary human immunodeficiency virus type 1 isolates resistant to soluble CD4 (sCD4) neutralization differ in sCD4 binding and glycoprotein gp120 retention from sCD4-sensitive isolates.
  per: Moore, J P, et al.
  Publicat: (1992)
• Mechanisms of human immunodeficiency virus Type 1 (HIV-1) neutralization: irreversible inactivation of infectivity by anti-HIV-1 antibody.
  per: McDougal, J S, et al.
  Publicat: (1996)
• A monoclonal antibody to CD4 domain 2 blocks soluble CD4-induced conformational changes in the envelope glycoproteins of human immunodeficiency virus type 1 (HIV-1) and HIV-1 infection of CD4+ cells.
  per: Moore, J P, et al.
  Publicat: (1992)
• Effects of changes in gp120-CD4 binding affinity on human immunodeficiency virus type 1 envelope glycoprotein function and soluble CD4 sensitivity.
  per: Thali, M, et al.
  Publicat: (1991)
• Myeloma-like cast nephropathy caused by human recombinant soluble CD4 (sCD4) in monkeys.
  per: Bugelski, P. J., et al.
  Publicat: (1992)