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Loss of expression of HDAC-recruiting methyl-CpG-binding domain proteins in human cancer
Dysregulation of CpG-methylation is a common feature of many human cancers and tumour suppressor genes can be silenced by hypermethylation. Recently, 2 methyl-CpG-binding domain proteins have been linked to gene inactivation by their ability to recruit co-repressors and HDAC-activity to methylated g...
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| Κύριοι συγγραφείς: | , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Nature Publishing Group
2001
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2375156/ https://ncbi.nlm.nih.gov/pubmed/11710831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.2041 |
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