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The topology of plasminogen binding and activation on the surface of human breast cancer cells
The urokinase-dependent activation of plasminogen by breast cancer cells plays an important role in metastasis. We have previously shown that the metastatic breast cancer cell line MDA-MB-231 over-expresses urokinase and binds and efficiently activates plasminogen at the cell surface compared to non...
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Format: | Artigo |
Sprache: | Inglês |
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Nature Publishing Group
2001
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2375062/ https://ncbi.nlm.nih.gov/pubmed/11556845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.2022 |
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