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The topology of plasminogen binding and activation on the surface of human breast cancer cells

The urokinase-dependent activation of plasminogen by breast cancer cells plays an important role in metastasis. We have previously shown that the metastatic breast cancer cell line MDA-MB-231 over-expresses urokinase and binds and efficiently activates plasminogen at the cell surface compared to non...

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Detalhes bibliográficos
Main Authors: Andronicos, N M, Ranson, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375062/
https://ncbi.nlm.nih.gov/pubmed/11556845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.2022
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