Characterization of heterotypic interaction effects in vitro to deconvolute global gene expression profiles in cancer

BACKGROUND: Perturbations in cell-cell interactions are a key feature of cancer. However, little is known about the systematic effects of cell-cell interaction on global gene expression in cancer. RESULTS: We used an ex vivo model to simulate tumor-stroma interaction by systematically co-cultivating...

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Main Authors: Buess, Martin, Nuyten, Dimitry SA, Hastie, Trevor, Nielsen, Torsten, Pesich, Robert, Brown, Patrick O
格式: Artigo
語言:Inglês
出版: BioMed Central 2007
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375029/
https://ncbi.nlm.nih.gov/pubmed/17868458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2007-8-9-r191
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