1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene (p,p'-DDE) disrupts the estrogen-androgen balance regulating the growth of hormone-dependent breast cancer cells

INTRODUCTION: Estrogen and androgen signalling pathways exert opposing influences on the proliferation of mammary epithelial and hormone-dependent breast cancer cells. We previously reported that plasma concentrations of 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene (p,p'-DDE), the main metaboli...

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Bibliographic Details
Main Authors: Aubé, Michel, Larochelle, Christian, Ayotte, Pierre
Format: Artigo
Language:Inglês
Published: BioMed Central 2008
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374972/
https://ncbi.nlm.nih.gov/pubmed/18275596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1862
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