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Brca1 breast tumors contain distinct CD44(+)/CD24(- )and CD133(+ )cells with cancer stem cell characteristics
INTRODUCTION: Whether cancer stem cells occur in BRCA1-associated breast cancer and contribute to therapeutic response is not known. METHODS: We generated and characterized 16 cell lines from five distinct Brca1deficient mouse mammary tumors with respect to their cancer stem cell characteristics. RE...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2374965/ https://ncbi.nlm.nih.gov/pubmed/18241344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1855 |
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