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Brca1 breast tumors contain distinct CD44(+)/CD24(- )and CD133(+ )cells with cancer stem cell characteristics

INTRODUCTION: Whether cancer stem cells occur in BRCA1-associated breast cancer and contribute to therapeutic response is not known. METHODS: We generated and characterized 16 cell lines from five distinct Brca1deficient mouse mammary tumors with respect to their cancer stem cell characteristics. RE...

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Detalhes bibliográficos
Main Authors: Wright, Mollie H, Calcagno, Anna Maria, Salcido, Crystal D, Carlson, Marisa D, Ambudkar, Suresh V, Varticovski, Lyuba
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374965/
https://ncbi.nlm.nih.gov/pubmed/18241344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1855
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