Attenuation of Venezuelan equine encephalitis virus strain TC-83 is encoded by the 5'-noncoding region and the E2 envelope glycoprotein.

The virulent Trinidad donkey (TRD) strain of Venezuelan equine encephalitis (VEE) virus and its live attenuated vaccine derivative, TC-83 virus, have different neurovirulence characteristics. A full-length cDNA clone of the TC-83 virus genome was constructed behind the bacteriophage T7 promoter in t...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Kinney, R M, Chang, G J, Tsuchiya, K R, Sneider, J M, Roehrig, J T, Woodward, T M, Trent, D W
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237493/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7679745/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.3.1269-1277.1993
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