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Fibrinogen Binding Sites P(336) and Y(338) of Clumping Factor A Are Crucial for Staphylococcus aureus Virulence

We have earlier shown that clumping factor A (ClfA), a fibrinogen binding surface protein of Staphylococcus aureus, is an important virulence factor in septic arthritis. When two amino acids in the ClfA molecule, P(336) and Y(338), were changed to serine and alanine, respectively, the fibrinogen bin...

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Bibliografische gegevens
Hoofdauteurs: Josefsson, Elisabet, Higgins, Judy, Foster, Timothy J., Tarkowski, Andrej
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2008
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374910/
https://ncbi.nlm.nih.gov/pubmed/18493318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002206
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