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The Effect of 24S-Hydroxycholesterol on Cholesterol Homeostasis in Neurons: Quantitative Changes to the Cortical Neuron Proteome

In human the brain represents only about 2% of the body’s mass but contains about one quarter of the body’s free cholesterol. Cholesterol is synthesised de novo in brain, and removed by metabolism to oxysterols. 24S-Hydoxycholesterol represents the major metabolic product of cholesterol in brain, be...

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Autors principals: Wang, Yuqin, Muneton, Sabina, Sjövall, Jan, Jovanovic, Jasmina N., Griffiths, William J.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374888/
https://ncbi.nlm.nih.gov/pubmed/18303831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr7006076
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