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The Goldbeter-Koshland Switch in the First-Order Region and Its Response to Dynamic Disorder
In their classical work (Proc. Natl. Acad. Sci. USA, 1981, 78:6840–6844), Goldbeter and Koshland mathematically analyzed a reversible covalent modification system which is highly sensitive to the concentration of effectors. Its signal-response curve appears sigmoidal, constituting a biochemical swit...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Public Library of Science
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2374878/ https://ncbi.nlm.nih.gov/pubmed/18478088 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002140 |
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