Identification of an immunodominant linear neutralization domain on the S2 portion of the murine coronavirus spike glycoprotein and evidence that it forms part of complex tridimensional structure.

Numerous studies have demonstrated that the spike glycoprotein of coronaviruses bears major determinants of pathogenesis. To elucidate the antigenic structure of the protein, a panel of monoclonal antibodies was studied by competitive ELISA, and their reactivities were assayed against fragments of t...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Daniel, C, Anderson, R, Buchmeier, M J, Fleming, J O, Spaan, W J, Wege, H, Talbot, P J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237483/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7679743/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.3.1185-1194.1993
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