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Epigenetic Silencing of Maspin Expression Occurs Early in the Conversion of Keratocytes to Fibroblasts

Maspin, a 42 kDa non-classical serpin (serine protease inhibitor) that controls cell migration and invasion, is mainly expressed by epithelial-derived cells but is also expressed in corneal stromal keratocytes. Upon culture of stromal keratocytes in the presence of FBS, maspin is down regulated to n...

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Detalhes bibliográficos
Main Authors: Horswill, Mark A., Narayan, Malathi, Warejcka, Debra J., Cirillo, Lisa A., Twining, Sally S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374753/
https://ncbi.nlm.nih.gov/pubmed/18291368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2008.01.003
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