The rate of the founder Jewish mutations in BRCA1 and BRCA2 in prostate cancer patients in Israel

Inherited predisposition occurs in 5–10% of all prostate cancer (CaP) patients, but the genes involved in conferring genetic susceptibility remain largely unknown. Several lines of evidence indicate that germline mutations in BRCA1 and BRCA2 might be associated with an increased risk for CaP. Three...

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Hlavní autoři: Vazina, A, Baniel, J, Yaacobi, Y, Shtriker, A, Engelstein, D, Leibovitz, I, Zehavi, M, Sidi, A A, Ramon, Y, Tischler, T, Livne, P M, Friedman, E
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2000
Témata:
Regular Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374645/
https://ncbi.nlm.nih.gov/pubmed/10945492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1249
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