Bench-to-bedside review: The inflammation-perpetuating pattern-recognition receptor RAGE as a therapeutic target in sepsis

Sepsis still represents an important clinical and economic challenge for intensive care units. Severe complications like multi-organ failure with high mortality and the lack of specific diagnostic tools continue to hamper the development of improved therapies for sepsis. Fundamental questions regard...

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Bibliographic Details
Main Authors: Bopp, Christian, Bierhaus, Angelika, Hofer, Stefan, Bouchon, Axel, Nawroth, Peter P, Martin, Eike, Weigand, Markus A
Format: Artigo
Language:Inglês
Published: BioMed Central 2008
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374592/
https://ncbi.nlm.nih.gov/pubmed/18226173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc6164
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