A phase I and pharmacokinetic study of the combination of capecitabine and docetaxel in patients with advanced solid tumours

Capecitabine and docetaxel are both active against a variety of solid tumours, while their toxicity profiles only partly overlap. This phase I study was performed to determine the maximum tolerated dose (MTD) and side-effects of the combination, and to establish whether there is any pharmacokinetic...

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Autors principals: Pronk, L C, Vasey, P, Sparreboom, A, Reigner, B, Planting, A S Th, Gordon, R J, Osterwalder, B, Verweij, J, Twelves, C
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2000
Matèries:
Regular Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374547/
https://ncbi.nlm.nih.gov/pubmed/10883663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1160
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