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Direct activation of oestrogen receptor- α by interleukin-6 in primary cultures of breast cancer epithelial cells

Interleukin 6 (IL-6) is secreted by breast tumours and shows synergistic activity with 17β-oestradiol (E2), leading to increases in reductive 17β-hydroxysteroid dehydrogenase activity in breast cancer epithelial cells. However, the mechanisms involved are poorly understood. Using short-term epitheli...

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Main Authors: Speirs, V, Kerin, M J, Walton, D S, Newton, C J, Desai, S B, Atkin, S L
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374478/
https://ncbi.nlm.nih.gov/pubmed/10755407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.1999.1097
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