Extensive molecular screening for hereditary non-polyposis colorectal cancer

The genetic abnormalities underlying hereditary non-polyposis colorectal cancer (HNPCC) are germline mutations in one of five DNA mismatch repair genes or in the TGFβRII gene. The aim of our study was to evaluate the significance of simple tests performed on tumours to select appropriate candidates...

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Detalhes bibliográficos
Main Authors: Dieumegard, B, Grandjouan, S, Sabourin, J-C, Bihan, M-L Le, Lefrère, I, Bellefqih, Pignon, J-P, Rougier, P, Lasser, P, Bénard, J, Couturier, D, Bressac-de Paillerets, B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2000
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374417/
https://ncbi.nlm.nih.gov/pubmed/10732761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.1999.1014
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