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Increased type-IV collagenase (MMP-2 and MMP-9) activity following preoperative radiotherapy in rectal cancer

The aim of this study was to investigate the effect of preoperative high-dose radiotherapy (25 Gy in 5 fractions over 5 days) on the type-IV collagenase protein profile, in patients with resectable rectal cancer, by gelatin zymography. Biopsy samples of tumour and distant normal mucosa from 12 patie...

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Detalhes bibliográficos
Main Authors: Kumar, A, Collins, H M, Scholefield, J H, Watson, S A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374410/
https://ncbi.nlm.nih.gov/pubmed/10732772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.1999.1025
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