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High–resolution crystal structure of deoxy hemoglobin complexed with a potent allosteric effector

The crystal structure of human deoxy hemoglobin (Hb) complexed with a potent allosteric effector (2-[4-[[(3,5-dimethylanilino)carbonyl]methyl]phenoxy]-2-methylpropionic acid) = RSR-13) is reported at 1.85 Å resolution. Analysis of the hemoglobin:effector complex indicates that two of these molecules...

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Main Authors: Safo, Martin K., Moure, Carmen M., Burnett, James C., Joshi, Gajanan S., Abraham, Donald J.
格式: Artigo
語言:Inglês
出版: Cold Spring Harbor Laboratory Press 2001
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374193/
https://ncbi.nlm.nih.gov/pubmed/11316875
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