A unique mitigator sequence determines the species specificity of the major late promoter in adenovirus type 12 DNA.

Human adenovirus type 12 (Ad12) cannot replicate in hamster cells, whereas human cells are permissive for Ad12. Ad12 DNA replication and late-gene and virus-associated RNA expression are blocked in hamster cells. Early Ad12 genes are transcribed, and the viral DNA can be integrated into the host gen...

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Bibliographic Details
Main Authors: Zock, C, Iselt, A, Doerfler, W
Format: Artigo
Language:Inglês
Published: 1993
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC237419/
https://ncbi.nlm.nih.gov/pubmed/8419643
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