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A unique mitigator sequence determines the species specificity of the major late promoter in adenovirus type 12 DNA.

Human adenovirus type 12 (Ad12) cannot replicate in hamster cells, whereas human cells are permissive for Ad12. Ad12 DNA replication and late-gene and virus-associated RNA expression are blocked in hamster cells. Early Ad12 genes are transcribed, and the viral DNA can be integrated into the host gen...

Ausführliche Beschreibung

Gespeichert in:
Bibliografische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Zock, C, Iselt, A, Doerfler, W
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1993
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237419/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8419643/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.2.682-693.1993
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