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Random circular permutation leading to chain disruption within and near α helices in the catalytic chains of aspartate transcarbamoylase: Effects on assembly, stability, and function

A collection of circularly permuted catalytic chains of aspartate transcarbamoylase (ATCase) has been generated by random circular permutation of the pyrB gene. From the library of ATCases containing permuted polypeptide chains, we have chosen for further investigation nine ATCase variants whose cat...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Beernink, Peter T., Yang, Ying R., Graf, Roney, King, David S., Shah, Shaival S., Schachman, Howard K.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2001
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374132/
https://ncbi.nlm.nih.gov/pubmed/11344321
Tagiau: Ychwanegu Tag
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