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Structure determination of human and murine β-defensins reveals structural conservation in the absence of significant sequence similarity

Defensins are cationic and cysteine-rich peptides that play a crucial role in the host defense against microorganisms of many organisms by their capability to permeabilize bacterial membranes. The low sequence similarity among the members of the large mammalian β-defensin family suggests that their...

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Bibliographic Details
Main Authors: Bauer, Finn, Schweimer, Kristian, Klüver, Enno, Conejo-Garcia, Jose-Ramon, Forssmann, Wolf-Georg, Rösch, Paul, Adermann, Knut, Sticht, Heinrich
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2001
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374044/
https://ncbi.nlm.nih.gov/pubmed/11714914
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