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Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core region of a β-trefoil
Human acidic fibroblast growth factor (FGF-1) is a member of the β-trefoil hyperfamily and exhibits a characteristic threefold symmetry of the tertiary structure. However, evidence of this symmetry is not readily apparent at the level of the primary sequence. This suggests that while selective press...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2001
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2374030/ https://ncbi.nlm.nih.gov/pubmed/11714927 |
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