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Sequencing of the ddl gene and modeling of the mutated D-alanine:D-alanine ligase in glycopeptide-dependent strains of Enterococcus faecium

Glycopeptide dependence for growth in enterococci results from mutations in the ddl gene that inactivate the host D-Ala:D-Ala ligase. The strains require glycopeptides as inducers for synthesis of resistance proteins, which allows for the production of peptidoglycan precursors ending in D-Ala-D-Lac...

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Bibliografske podrobnosti
Main Authors: Gholizadeh, Y., Prevost, M., Van Bambeke, F., Casadewall, B., Tulkens, P.M., Courvalin, P.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2001
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373979/
https://ncbi.nlm.nih.gov/pubmed/11274474
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