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Structure-activity relationship for adenosine kinase from Mycobacterium tuberculosis: II. Modifications to the ribofuranosyl moiety
Adenosine kinase (Ado kinase) from Mycobacterium tuberculosis is structurally and biochemically unique from other known Ado kinases. This purine salvage enzyme catalyzes the first step in the conversion of the adenosine analog, 2-methyl-Ado (methyl-Ado), into a metabolite with antitubercular activit...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2373907/ https://ncbi.nlm.nih.gov/pubmed/18329005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2008.01.007 |
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