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Hybrid optimization method with general switching strategy for parameter estimation

BACKGROUND: Modeling and simulation of cellular signaling and metabolic pathways as networks of biochemical reactions yields sets of non-linear ordinary differential equations. These models usually depend on several parameters and initial conditions. If these parameters are unknown, results from sim...

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Bibliografiske detaljer
Main Authors: Balsa-Canto, Eva, Peifer, Martin, Banga, Julio R, Timmer, Jens, Fleck, Christian
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373877/
https://ncbi.nlm.nih.gov/pubmed/18366722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-2-26
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