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Microphthalmia and cataract in rats with a novel point mutation in connexin 50 - L7Q

PURPOSE: We isolated an autosomal semi-dominant cataract from our inbred SHR/OlaIpcv rat colony. Heterozygotes express pulverulent cataract with smaller eyes; homozygotes express marked microphthalmia with hypoplastic lens. We call this mutation Dca (for dominant cataract). In this study, we focus o...

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Bibliografiske detaljer
Main Authors: Liška, František, Chylíková, Blanka, Martínek, Jindřich, Křen, Vladimír
Format: Artigo
Sprog:Inglês
Udgivet: Molecular Vision 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373795/
https://ncbi.nlm.nih.gov/pubmed/18470322
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