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Characterization of binding-induced changes in dynamics suggests a model for sequence-nonspecific binding of ssDNA by replication protein A

Single-stranded-DNA-binding proteins (SSBs) are required for numerous genetic processes ranging from DNA synthesis to the repair of DNA damage, each of which requires binding with high affinity to ssDNA of variable base composition. To gain insight into the mechanism of sequence-nonspecific binding...

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Autori principali: Bhattacharya, Shibani, Botuyan, Maria-Victoria, Hsu, Fred, Shan, Xi, Arunkumar, A.I., Arrowsmith, Cheryl H., Edwards, Aled M., Chazin, Walter J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373701/
https://ncbi.nlm.nih.gov/pubmed/12237454
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