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Protein stability indicates divergent evolution of PD-(D/E)XK type II restriction endonucleases

Type II restriction endonucleases recognize 4–8 base-pair-long DNA sequences and catalyze their cleavage with remarkable specificity. Crystal structures of the PD-(DE)XK superfamily revealed a common α/β core motif and similar active site. In contrast, these enzymes show little sequence similarity a...

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Bibliografski detalji
Glavni autori: Fuxreiter, Monika, Simon, István
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2002
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373676/
https://ncbi.nlm.nih.gov/pubmed/12142452
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