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Protein stability indicates divergent evolution of PD-(D/E)XK type II restriction endonucleases
Type II restriction endonucleases recognize 4–8 base-pair-long DNA sequences and catalyze their cleavage with remarkable specificity. Crystal structures of the PD-(DE)XK superfamily revealed a common α/β core motif and similar active site. In contrast, these enzymes show little sequence similarity a...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2002
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2373676/ https://ncbi.nlm.nih.gov/pubmed/12142452 |
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