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Defect in IgV gene somatic hypermutation in Common Variable Immuno-Deficiency syndrome

Common Variable Immuno-Deficiency (CVID) is the most common symptomatic primary antibody-deficiency syndrome, but the basic immunologic defects underlying this syndrome are not well defined. We report here that among eight patients studied (six CVID and two hypogammaglobulinemic patients with recurr...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Levy, Yves, Gupta, Neetu, Le Deist, Françoise, Garcia, Corinne, Fischer, Alain, Weill, Jean-Claude, Reynaud, Claude-Agnès
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1998
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23736/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9789054/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.22.13135
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