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Impact of domain interchange on conformational stability and equilibrium folding of chimeric class μ glutathione transferases

Rat μ class glutathione transferases M1-1 and M2-2 are homodimers that share a 78% sequence identity but display differences in stability. M1-1 is more stable at the secondary and tertiary structural levels, whereas its quaternary structure is less stable. Each subunit in these proteins consists of...

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Main Authors: Luo, Jiann-Kae, Hornby, Judith A.T., Wallace, Louise A., Chen, Jihong, Armstrong, Richard N., Dirr, Heini W.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373595/
https://ncbi.nlm.nih.gov/pubmed/12192076
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