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α(1)-Proteinase inhibitor mutants with specificity for plasma kallikrein and C1s but not C1

Coagulation and complement proteinases are activated in sepsis, and one approach to therapy is to develop proteinase inhibitors that will specifically inhibit these proteinases without inhibiting activated protein C, a proteinase that is beneficial to survival. In this study, we made mutants of the...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sulikowski, Thomas, Bauer, Bryan A., Patston, Philip A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2002
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373593/
https://ncbi.nlm.nih.gov/pubmed/12192078
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