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Inhibition of herpes simplex virus type 1 DNA polymerase activity by peptides from the UL42 accessory protein is largely nonspecific.

To identify regions in the UL42 protein of herpes simplex virus type 1 which affect viral DNA polymerase activity, a series of 96 overlapping pentadecapeptides spanning the entire 488 amino acids of the UL42 protein were synthesized and tested for their ability to inhibit polymerase activity on a pr...

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Autores principales: Owsianka, A M, Hart, G, Murphy, M, Gottlieb, J, Boehme, R, Challberg, M, Marsden, H S
Formato: Artigo
Lenguaje:Inglês
Publicado: 1993
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC237359/
https://ncbi.nlm.nih.gov/pubmed/8380075
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