Inhibition of herpes simplex virus type 1 DNA polymerase activity by peptides from the UL42 accessory protein is largely nonspecific.

To identify regions in the UL42 protein of herpes simplex virus type 1 which affect viral DNA polymerase activity, a series of 96 overlapping pentadecapeptides spanning the entire 488 amino acids of the UL42 protein were synthesized and tested for their ability to inhibit polymerase activity on a pr...

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Pubblicato in:	J Virol
Autori principali:	Owsianka, A M, Hart, G, Murphy, M, Gottlieb, J, Boehme, R, Challberg, M, Marsden, H S
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1993
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237359/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8380075/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.1.258-264.1993
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