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MS-DOCK: Accurate multiple conformation generator and rigid docking protocol for multi-step virtual ligand screening

BACKGROUND: The number of protein targets with a known or predicted tri-dimensional structure and of drug-like chemical compounds is growing rapidly and so is the need for new therapeutic compounds or chemical probes. Performing flexible structure-based virtual screening computations on thousands of...

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Detalhes bibliográficos
Main Authors: Sauton, Nicolas, Lagorce, David, Villoutreix, Bruno O, Miteva, Maria A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373571/
https://ncbi.nlm.nih.gov/pubmed/18402678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-184
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