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Effects of molecular crowding by saccharides on α-chymotrypsin dimerization

Given the importance of protein complexes as therapeutic targets, it is necessary to understand the physical chemistry of these interactions under the crowded conditions that exist in cells. We have used sedimentation equilibrium to quantify the enhancement of the reversible homodimerization of α-ch...

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Detalhes bibliográficos
Main Authors: Patel, Chetan N., Noble, Schroeder M., Weatherly, Gresham T., Tripathy, Ashutosh, Winzor, Donald J., Pielak, Gary J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373554/
https://ncbi.nlm.nih.gov/pubmed/11967357
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