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The interdigitated β-helix domain of the P22 tailspike protein acts as a molecular clamp in trimer stabilization

The P22 tailspike adhesin is an elongated thermostable trimer resistant to protease digestion and to denaturation in sodium dodecyl sulfate. Monomeric, dimeric, and protrimeric folding and assembly intermediates lack this stability and are thermolabile. In the native trimer, three right-handed paral...

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Detalhes bibliográficos
Main Authors: Kreisberg, Jason F., Betts, Scott D., Haase-Pettingell, Cameron, King, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373520/
https://ncbi.nlm.nih.gov/pubmed/11910025
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