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Mice deficient in involucrin, envoplakin, and periplakin have a defective epidermal barrier

The cornified envelope is assembled from transglutaminase cross-linked proteins and lipids in the outermost epidermal layers and is essential for skin barrier function. Involucrin, envoplakin, and periplakin form the protein scaffold on which the envelope assembles. To examine their combined functio...

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Autors principals: Sevilla, Lisa M., Nachat, Rachida, Groot, Karen R., Klement, John F., Uitto, Jouni, Djian, Philippe, Määttä, Arto, Watt, Fiona M.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373502/
https://ncbi.nlm.nih.gov/pubmed/18166659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200706187
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