Huntingtin-interacting protein 14, a palmitoyl transferase required for exocytosis and targeting of CSP to synaptic vesicles

Posttranslational modification through palmitoylation regulates protein localization and function. In this study, we identify a role for the Drosophila melanogaster palmitoyl transferase Huntingtin-interacting protein 14 (HIP14) in neurotransmitter release. hip14 mutants show exocytic defects at low...

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Detalhes bibliográficos
Main Authors: Ohyama, Tomoko, Verstreken, Patrik, Ly, Cindy V., Rosenmund, Tanja, Rajan, Akhila, Tien, An-Chi, Haueter, Claire, Schulze, Karen L., Bellen, Hugo J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373489/
https://ncbi.nlm.nih.gov/pubmed/18158335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200710061
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