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The active site of hydroxynitrile lyase from Prunus amygdalus: Modeling studies provide new insights into the mechanism of cyanogenesis

The FAD-dependent hydroxynitrile lyase from almond (Prunus amygdalus, PaHNL) catalyzes the cleavage of R-mandelonitrile into benzaldehyde and hydrocyanic acid. Catalysis of the reverse reaction—the enantiospecific formation of α-hydroxynitriles—is now widely utilized in organic syntheses as one of t...

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Bibliografski detalji
Glavni autori: Dreveny, Ingrid, Kratky, Christoph, Gruber, Karl
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2002
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373431/
https://ncbi.nlm.nih.gov/pubmed/11790839
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