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N-Linked Glycosylation Is Required for Nicotinic Receptor Assembly but Not for Subunit Associations with Calnexin

We investigated how asparagine (N)-linked glycosylation affects assembly of acetylcholine receptors (AChRs) in the endoplasmic reticulum (ER). Block of N-linked glycosylation inhibited AChR assembly whereas block of glucose trimming partially blocked assembly at the late stages. Removal of each of s...

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Detalhes bibliográficos
Main Authors: Wanamaker, Christian P., Green, William N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373277/
https://ncbi.nlm.nih.gov/pubmed/16091366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M501813200
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