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Hepatitis C virus polyprotein processing: kinetics and mutagenic analysis of serine proteinase-dependent cleavage.

Hepatitis C virus (HCV) serine proteinase (Cpro-2) is responsible for the processing of HCV nonstructural (NS) protein processing. To clarify the mechanism of Cpro-2-dependent processing, pulse-chase and mutation analyses were performed by using a transient protein production system in cultured cell...

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Bibliographic Details
Published in:J Virol
Main Authors: Tanji, Y, Hijikata, M, Hirowatari, Y, Shimotohno, K
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1994
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237315/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7966638/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.12.8418-8422.1994
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