A cis-acting function for the coronavirus leader in defective interfering RNA replication.

To test the hypothesis that the 65-nucleotide (nt) leader on subgenomic mRNAs suffices as a 5'-terminal cis-acting signal for RNA replication, a corollary to the notion that coronavirus mRNAs behave as replicons, synthetic RNA transcripts of a cloned, reporter-containing N mRNA (mRNA 7) of the...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Chang, R Y, Hofmann, M A, Sethna, P B, Brian, D A
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1994
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237289/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7966615/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.12.8223-8231.1994
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