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Two open reading frames (ORF1 and ORF2) within the 2.0-kilobase latency-associated transcript of herpes simplex virus type 1 are not essential for reactivation from latency.

The herpes simplex virus type 1 (HSV-1) latency-associated transcripts (LATs) are dispensable for establishment and maintenance of latent infection. However, the LATs have been implicated in reactivation of the virus from its latent state. Since the reported LAT deletion and/or insertion variants th...

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Опубликовано в::J Virol
Главные авторы: Fareed, M U, Spivack, J G
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 1994
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237271/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7966597/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.12.8071-8081.1994
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