Prolonged production of NADPH oxidase-corrected granulocytes after gene therapy of chronic granulomatous disease

Little is known about the potential for engraftment of autologous hematopoietic stem cells in human adults not subjected to myeloablative conditioning regimens. Five adult patients with the p47(phox) deficiency form of chronic granulomatous disease received intravenous infusions of autologous CD34(+...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Malech, Harry L., Maples, Phillip B., Whiting-Theobald, Narda, Linton, Gilda F., Sekhsaria, Sudhir, Vowells, Sarah J., Li, Fei, Miller, Judi A., DeCarlo, Ellen, Holland, Steven M., Leitman, Susan F., Carter, Charles S., Butz, Robert E., Read, Elizabeth J., Fleisher, Thomas A., Schneiderman, Richard D., Van Epps, Dennis E., Spratt, S. Kaye, Maack, Christopher A., Rokovich, Joseph A., Cohen, Lawrence K., Gallin, John I.
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1997
Sujets:	Biological Sciences
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23727/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9342375/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.22.12133
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